What? I really don't understand people who only want to play as their own (or the other) gender. Okay it might be more immersive or a better fantasy for you personally, but it really won't change the game, like at all. (Unless they have gender-specific storylines and stuff but you know what I mean.)
Edit: I'm talking about single player, story driven games btw. It's fine to skip a multiplayer game because of a lack of a certain gender where it doesn't make sense not to have it there, like older CODs, Arcana Heart etc IMO.