Well, RPG is a really flexible description. I would say "The Outer Worlds" is the only RPG in the last few years, that makes constantly fun of itself. Quite a good ride with your ship "The Unreliable", who doesn't want to make a trip on such a ship
I also would say outer worlds. It’s gameplay is very much in the Bethesda Skyrim/Fallout vein though. Just a word of advice I would try to play it in a device with and SSD as the load times are long and frequent.
Jagged Alliance 2 provided some well rounded humor. But you need steel nerves to play it nowadays. Even with the so called "make it better" patches, it's pacing is off.