Great news. One little caveat, for now...
Known issues
Split-screen
Split-screen is known to render incorrectly in Unreal Engine 4 and to crash with the native DirectX® 12 and Vulkan® backends in Unreal Engine 5. This will be fixed in a future release.
Of all the issues that a tech could be saddled with, why's it gotta be that a cool new thing ends up making Split-Screen harder?!
(*Kidding, sort of, as this should be only a temporary issue, plus it does make sense why a temporal upscaling approach might have trouble with two or more separate screen divisions. But it does catch my heart a bit when I read something about split-screen these days, as it's usually a negative. So many developers have just abandoned split-screen multiplayer in games, and modern engines like Unreal have in the past a bad reputation for making split-screen hard to develop, although Gears has continued to offer splits though Gears 1-3 and even 4/5, so Epic has tried to prove it doable. Split-screen is a great feature in the right games and I hope nothing ever breaks it up.)